ly 6-14 hours, after which time they leave the circulation and pass into the tissue pool. The circulating time is shortened during acute infections as neutrophils pass to the site of infection in the tissues. The main function of the neutrophil is the phagocytosis of pyogenic bacteria.
Lymphoid primitive stem cells divide and differentiate into pre-B lymphocytes and pre-T lymphocytes in the bone marrow. Pre-T lymphocytes mature and proliferate into T cells in the thymus. Pre-B cells proliferate in the bone marrow and migrate to peripheral lymphoid organs (spleen and lymph nodes) where further proliferation takes place.
Platelets are produced from the cytoplasm of megakaryocytes
Once in the circulation, platelets survive for 8-12 days. Up to 20-30% of circulating platelets can be sequestered in the spleen; the figure may be a high as 90% if there is splenomegaly.
Old or damaged platelets are removed from the circulation by the spleen, liver and bone marrow.
Veterinary Clinical Pathology兽医临床病理学下载地址